cartouche ECN WORKSHOP
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Abstracts

Oral communications

1

2026 - Oral communication

Crystal-Induced Inflammation

The role of osmolarity and LRRC8A channel in cartilage homeostasis and osteoarthritis

Yasmine Sedjai, Augustin Latourte, Mathilde Pezot, Eric Hay, Pascal Bizot, Mylène Zarka, Pascal Richette, Hang Korng Ea

2

2026 - Oral communication

Hyperuricemia and gout - treatment

Understanding gout management patterns among primary care physicians: systematic literature review and analysis

Paul Doghramji, Richard Lai, Alexis Woods, Salvador Brito, Niranjan Kathe, And Brian Lamoreaux

3

2026 - Oral communication

Crystal-Induced Inflammation

Do uric acid crystals activate the NLRP3 inflammasome?

Radomir Slominski; Marilyn E. Merriman ; Isidoro Cobo ; Tanecia Mitchell ; Joseph Crivelli; Chander Raman ; Richard Reynolds ; Tony R. Merriman.

4

2026 - Oral communication

Crystal-Induced Inflammation

Oxidative Stress and Cardiovascular Comorbidities in Gout: The Diagnostic Value of Allantoin and the Allantoin/Uric Acid Ratio

Blanka Stiburkova, Lenka Hasikova, Petr Kozlik, Kveta Kalikova, Marketa Pavlíkova

6

2026 - Oral communication

Crystal-Induced Inflammation

Characterization of giant multinucleated cells phenotype and formation in gouty tophus

Charles Leroy, Anne Dupont, Mylène Zarka, Nghia Pham, Huy Nguyen D.q, Augustin Latourte, Thomas Bardin, Pascal Richette, Hang Korng Ea

7

2026 - Oral communication

Crystal-Induced Inflammation

Distribution of calcium pyrophosphate crystal deposits on whole-body low-dose CT scan

Bùi Hoàng Anh, Alan Gauffenic, Augustin Latourte, Marina Assadourian, Pascal Richette, Valérie Bousson, Hang Korng Ea.

8

2026 - Oral communication

Crystal-Induced Inflammation

Targeted Demineralization of Sub-RPE Calcifications using Anti-Elastin DTPA-HSA Nanoparticles in a Progeroid Mouse Model

Frank Rutsch, Yvonne Nitschke, Theresa Begasse, Peter Heiduschka, Nicole Eter, Uwe Hansen, Joseph Deering, Marc Mckee, Klaus Langer

9

2026 - Oral communication

Hyperuricemia and gout - treatment

Urate is associated with both calcification and total atherosclerotic burden in coronary arteries: results from the SCAPIS study.

Drivelegka P 1, Jacobsson Lth 1, Forsblad D’elia H 1, Zverkova-Sandström T 1, Nilsson Pm 2, Fagman E 3, Söderberg S 4, Bergström G 5, Kapetanovic M 6, Dehlin M 1.

Posters

10

2026 - Poster

Mechanisms of Calcification

Toward a Federated, Platform for Harmonised Phenotyping and Longitudinal Study of Calcium Pyrophosphate Deposition Disease (CPPD)

Delphine S. Courvoisier 1,2, Tristan Pascart 3, Charlotte Jauffret 3, Hang-Korng Ea 4, Florian Kollert 5, Augustin Latourte 4, Kim Lauper 1,2

11

2026 - Poster

Miscellaneous and rare diseases

Magnesium depletion score is associated with arterial stiffness: data from the Brisighella Heart Study

Claudio Borghi, Federica Fogacci, Elisa Grandi, Sergio D’addato, Arrigo F.g. Cicero, On Behalf Of The Brisighella Heart Study Group

12

2026 - Poster

Hyperuricemia and gout - treatment

Phenotyping renal and metabolic hyperuricemia: what BSA-corrected eGFR reveals

Janis Timsans, Raine Tiihonen, Jenni Kauppi, Vappu Rantalaiho, Anne Kerola, Kia Hakkarainen, Tiina Lehto, Hannu Kautiainen, Markku Kauppi

13

2026 - Poster

Hyperuricemia and gout - treatment

A Pragmatic Allopurinol Dose Escalation Strategy to Achieve Serum Urate Target inULT–Naïve Gout Patients: A Real-World Experience

Patricio Cardoso-Peñafiel [1,2], Maria Fernanda Del Pino-Zambrano [1,2], Marta Novella-Navarro [2,3], Clara Siso-Hernandez 1, Celia Sanchez-Jimenez 1, Carolina Marín-Huertas [1,4], Laura Cebrián-Méndez [1,4], Leticia Lojo-Oliveira [1,4], Ana Pareja-Martinez [1,4], Almudena , Roman-Pascual [1,4], Carmen Olga Sanchez Gonzalez [1,4], Isabel Fuente-Ruiz 5, Teresa Navio-Marco [1,4], Enrique Calvo-Aranda [1,2,4]

14

2026 - Poster

Mechanisms of Calcification

Role of extracellular matrix in cartilage calcification in an ex vivo model using inorganic phosphate

Jasmin Bäuerle, Carolin Schneider, Agnieszka Halm-Pozniak, Christoph H Lohmann, Jessica Bertrand, Andrea Schwab

15

2026 - Poster

Crystal-Induced Inflammation

Robust monosodium urate crystal-induced transcriptomic changes in multiple human immune cell systems

Nicholas A Sumpter, Nils Asmann, Brenda Kischkel, Pariyaphon Lertprachakwong, Paloma M Guzzardo, Mayank Tanson, Stephane E Castel, Heather A Arnett, Jeffrey Edberg, Tony R Merriman, Leo A B Joosten, Richard Reynolds

16

2026 - Poster

Mechanisms of Calcification

Prevalence and factors associated to crowned dens (CD) and CD syndrome in patients with calcium pyrophosphate arthritis (CPPA)

Ana M. Herrero-Beites, Leire Suarez-Zorrilla, Elena Garmendia-Sanchez, Consuelo Modesto-Caballero, Fernando Perez-Ruiz

17

2026 - Poster

Hyperuricemia and gout - treatment

Serum urate during follow-up of gout is not associated to mortality in the lowest stratum

Ana M. Herrero-Beites (1)0, Nerea Perez-Herrero (2), Fernando Perez-Ruiz (3)

18

2026 - Poster

Mechanisms of Calcification

Plasma Pyrophosphate Hydrolysis Predicts Early Abdominal Aortic Aneurysm Growth

Sara Tallón-Lorenzo1, Juan Francisco Crespo-Cerezo1, Alicia Flores-Roco1,2, Jes S. Lindholt3, Jose Luis Martin-Ventura4,5, Ricardo Villa-Bellosta1,2,6

19

2026 - Poster

Hyperuricemia and gout - treatment

Acute kidney injury in gout: prevalence and risk factors through two decades

Nuria Perez-Herrero, Ana M. Herrero-Beites, Jose M. Urbizu-Gallardo, Fernando Perez-Ruiz

24

2026 - Poster

Hyperuricemia and gout - treatment

Analysis of allopurinol prescription suggests clinical inertia to increase doses

Fernando Perez-Ruiz*, Nerea Perez-Herrero**, Leire Marcos Fernandez***

25

2026 - Poster

Hyperuricemia and gout - treatment

Uric acid: a surprising protector of large joints? Lower incidence of large joint replacements among individuals with higher SUA

Janis Timsans, Raine Tiihonen, Jenni Kauppi, Vappu Rantalaiho, Anne Kerola, Kia Hakkarainen, Tiina Lehto, Hannu Kautiainen, Markku Kauppi

26

2026 - Poster

Crystal-Induced Inflammation

High oxalate diets stimulate crystalluria in healthy subjects and kidney stone patients

Vivek Verma Phd, Christine Wright Phd, Mary Doamekpor Bs, Sirisha Swamigari, Ms, Parveen Kumar Phd, Dean Assimos Md, And Tanecia Mitchell Phd

28

2026 - Poster

Hyperuricemia and gout - treatment

Understanding gout management patterns among primary care physicians: systematic literature review and analysis

Paul Doghramji, Richard Lai, Alexis Woods, Salvador Brito, Niranjan Kathe, Brian Lamoreaux

29

2026 - Poster

OA-Genetics and EUROGOUT-Inflammation

Epigenetic Profiling Reveals DNA Methylation Differences in PXE Fibroblasts

Abel Fothi, Francesco Demetrio Lofaro, Robbe Derudder, Alessia Mazzilli, Federica Boraldi, Olivier Vanakker, Daniela Quaglino, Tamas Aranyi

30

2026 - Poster

Hyperuricemia and gout - treatment

Subcutaneous tocilizumab in difficulttotreat tophaceous gout refractory to anakinra: areal-world case series

MF Del Pino Zambrano , P Cardoso Peñafiel, C Marín Huertas, L Cebrián Méndez, L Lojo Oliveira, A Pareja Martinez, A Román Pascual, O Sánchez González, C Siso Hernández, S Cruz Beltran, Mt Navío Marco, E Calvo Aranda

32

2026 - Poster

Hyperuricemia and gout - treatment

The Impact of Elevated Serum Urate Levels and Tophi on HRQOL and Daily Functioning in Patients with Uncontrolled Gout

Angelo Gaffo, Md1, Bhavisha Desai, Pharm D2, Abiola Oladapo, Phd2, Nana Kragh, Msc3, Lauren A. Do, Ms4, Madeline O’grady, Ma4, Naomi Schlesinger, Md5

33

2026 - Poster

Hyperuricemia and gout - treatment

Hyperuricemia is associated with higher coronary artery calcium score in type 2 diabetes patients

Andreia N. S. Hisi, Céline Chollet, Florence Castelli, François Fenaille, Tiphaine Vidal-Trécan, Jean-Pierre Riveline, Nicolas Venteclef, Pascal Richette, Augustin Latourte, Jean-François Gautier, Jean-Baptiste Julla, Hang-Korng Ea